RNA Details
Disease Name
nephritis interstitia
Tissue
kidney
RNA Symbol
LOC105375913
RNA ID
RNA Type
lncrna
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
NA
Target
NA
Pathway
MAPK SIGNALING PATHWAY
PubMed ID
Title
Upregulated long noncoding RNA LOC105375913 induces tubulointerstitial fibrosis in focal segmental glomerulosclerosis
Year
2019
Function
"The activation of C3a/p38/xbp-1s pathway induces the expression of loc105375913 in tubular cells,and loc105375913 increases the level of snail and induces tubulointerstitial fibrosis through competitive binding of miR-27b in tubular cells of focal segmental glomerulosclerosis patients."